ETF Copilot

HELX vs ITOT: holdings overlap, shared companies and scores

As of October 9, 2026, HELX and ITOT overlap 2.9% by weight. Franklin Genomic Advancements ETF (HELX): Genomics and gene therapy companies iShares Core S&P Total U.S. Stock Market ETF (ITOT): U.S. total market equities.

Updated October 9, 2026

Where HELX and ITOT trade against their own history

HELX trades at 29.5 times earnings, against its own median of 30.0, and is cheaper than 53% of its own last 5 years.

ITOT trades at 24.2 times earnings, against its own median of 22.3, and is more expensive than 63% of its own last 9 years.

What moved HELX and ITOT this week

HELX fell 2.6% in the week to October 9, 2026. The holdings that moved it most were Twist Bioscience (−15.3%), Guardant Health (−5.8%) and Adaptive Biotechnologies (−6.6%); Krystal Biotech (+2.9%) pushed the other way.

ITOT rose 1.0% in the week to October 9, 2026. The holdings that moved it most were Microsoft (+3.4%), Amazon.com (+4.3%) and Alphabet (+2.4%); Nvidia (−2.0%) pushed the other way.

What do HELX and ITOT each hold?

What's inside HELX: AI 4%, Tech 1%.

50% of HELX is its ten largest holdings.

What's inside ITOT: Tech 43%, Magnificent 7 31%.

35% of ITOT is its ten largest holdings.

How much do HELX and ITOT overlap? 2.9% by weight

As of October 9, 2026, HELX and ITOT overlap 2.9% by weight.

93% of HELX is already inside ITOT.

3% of ITOT is already inside HELX.

HELX holds 68 companies and ITOT holds 2,425; 56 are in both.

Computed by ETF Copilot from both funds' holdings rather than quoted from a data provider, and rebuilt nightly.

How does ETF Copilot score HELX and ITOT? 4.2 and 6.6 out of 10

As of October 9, 2026, ETF Copilot scores HELX 4.2 out of 10 and ITOT 6.6 out of 10.

They differ most on Quality: HELX 0.2 and ITOT 7.7.

The five factor scores behind them are set out below, 0–10 and higher is better, ranked against every US equity ETF we track.

HELX vs ITOT — ETF Copilot factor scores, 0–10
FactorHELXITOT
Growth9.77.2
Value4.93.0
Risk1.56.3
Quality0.27.7
Return2.67.7

ITOT is the cheaper of the two at 0.03% a year

As of October 9, 2026, HELX charges 0.50% a year, yields 0.35% and holds $29M in assets across 68 positions.

As of October 9, 2026, ITOT charges 0.03% a year, yields 0.99% and holds $97.8B in assets across 2425 positions.

HELX vs ITOT — cost, income and size
MeasureHELXITOT
Expense ratio0.50%0.03%
Dividend yield0.35%0.99%
Assets under management$29M$97.8B
Holdings682425

Expense ratio, dividend yield and assets under management are reported by the fund and refreshed daily. Every other figure on this page is computed by ETF Copilot.

Compare with similar funds

Cite this

ETF Copilot, “HELX vs ITOT holdings overlap and scores”, as of October 9, 2026.
https://etf-copilot.com/compare/helx-vs-itot

  1. Franklin Genomic Advancements ETF (HELX)
  2. iShares Core S&P Total U.S. Stock Market ETF (ITOT)

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