ETF Copilot

IYH vs XBI: holdings overlap, shared companies and scores

As of October 28, 2026, IYH and XBI overlap 13.8% by weight. iShares U.S. Healthcare ETF (IYH): U.S. healthcare sector stocks. State Street SPDR S&P Biotech ETF (XBI): U.S. biotech industry stocks.

Updated October 28, 2026

Where IYH trades against its own history

IYH trades at 33.5 times earnings, against its own median of 25.5, and is more expensive than 99% of its own last 9 years.

What moved IYH and XBI this week

IYH rose 0.8% in the week to October 28, 2026. The holdings that moved it most were Johnson & Johnson (+5.1%), Eli Lilly (+1.4%) and Amgen (+3.1%); Merck (−6.0%) pushed the other way.

XBI rose 3.1% in the week to October 28, 2026. The holdings that moved it most were Oruka Therapeutics (+20.1%), Twist Bioscience (+16.3%) and Grail (+19.1%); Moderna (−12.9%) pushed the other way.

What do IYH and XBI each hold?

What's inside IYH: AI 0%.

59% of IYH is its ten largest holdings.

18% of XBI is its ten largest holdings.

How much do IYH and XBI overlap? 13.8% by weight

As of October 28, 2026, IYH and XBI overlap 13.8% by weight.

24% of IYH is already inside XBI.

34% of XBI is already inside IYH.

IYH holds 103 companies and XBI holds 163; 24 are in both.

Computed by ETF Copilot from both funds' holdings rather than quoted from a data provider, and rebuilt nightly.

How does ETF Copilot score IYH and XBI? 5.4 and 4.9 out of 10

As of October 28, 2026, ETF Copilot scores IYH 5.4 out of 10 and XBI 4.9 out of 10.

They differ most on Risk: IYH 8.0 and XBI 1.2.

The five factor scores behind them are set out below, 0–10 and higher is better, ranked against every US equity ETF we track.

IYH vs XBI — ETF Copilot factor scores, 0–10
FactorIYHXBI
Growth6.39.8
Value0.7—
Risk8.01.2
Quality6.80.3
Return4.95.6

XBI is the cheaper of the two at 0.35% a year

As of October 28, 2026, IYH charges 0.37% a year, yields 1.07% and holds $4.5B in assets across 103 positions.

As of October 28, 2026, XBI charges 0.35% a year, yields 0.35% and holds $10.3B in assets across 163 positions.

IYH vs XBI — cost, income and size
MeasureIYHXBI
Expense ratio0.37%0.35%
Dividend yield1.07%0.35%
Assets under management$4.5B$10.3B
Holdings103163

Expense ratio, dividend yield and assets under management are reported by the fund and refreshed daily. Every other figure on this page is computed by ETF Copilot.

Compare with similar funds

Cite this

ETF Copilot, “IYH vs XBI holdings overlap and scores”, as of October 28, 2026.
https://etf-copilot.com/compare/iyh-vs-xbi

  1. iShares U.S. Healthcare ETF (IYH)
  2. State Street SPDR S&P Biotech ETF (XBI)

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