XBI vs XLV: holdings overlap, shared companies and scores
As of October 28, 2026, XBI and XLV overlap 9.7% by weight. State Street SPDR S&P Biotech ETF (XBI): U.S. biotech industry stocks. State Street Health Care Select Sector SPDR ETF (XLV): U.S. healthcare sector.
Updated October 28, 2026
Where XLV trades against its own history
XLV trades at 33.4 times earnings, against its own median of 25.1, and is more expensive than 98% of its own last 9 years.
What moved XBI this week
XBI rose 3.1% in the week to October 28, 2026. The holdings that moved it most were Oruka Therapeutics (+20.1%), Twist Bioscience (+16.3%) and Grail (+19.1%); Moderna (−12.9%) pushed the other way.
What do XBI and XLV each hold?
18% of XBI is its ten largest holdings.
What's inside XLV: AI 0%.
61% of XLV is its ten largest holdings.
How much do XBI and XLV overlap? 9.7% by weight
As of October 28, 2026, XBI and XLV overlap 9.7% by weight.
13% of XBI is already inside XLV.
20% of XLV is already inside XBI.
XBI holds 163 companies and XLV holds 61; 8 are in both.
Computed by ETF Copilot from both funds' holdings rather than quoted from a data provider, and rebuilt nightly.
How does ETF Copilot score XBI and XLV? 4.9 and 5.4 out of 10
As of October 28, 2026, ETF Copilot scores XBI 4.9 out of 10 and XLV 5.4 out of 10.
They differ most on Risk: XBI 1.2 and XLV 8.3.
The five factor scores behind them are set out below, 0–10 and higher is better, ranked against every US equity ETF we track.
| Factor | XBI | XLV |
|---|---|---|
| Growth | 9.8 | 5.8 |
| Risk | 1.2 | 8.3 |
| Quality | 0.3 | 6.9 |
| Return | 5.6 | 5.3 |
XLV is the cheaper of the two at 0.08% a year
As of October 28, 2026, XBI charges 0.35% a year, yields 0.35% and holds $10.3B in assets across 163 positions.
As of October 28, 2026, XLV charges 0.08% a year, yields 1.42% and holds $47.0B in assets across 61 positions.
| Measure | XBI | XLV |
|---|---|---|
| Expense ratio | 0.35% | 0.08% |
| Dividend yield | 0.35% | 1.42% |
| Assets under management | $10.3B | $47.0B |
| Holdings | 163 | 61 |
Expense ratio, dividend yield and assets under management are reported by the fund and refreshed daily. Every other figure on this page is computed by ETF Copilot.
Compare with similar funds
Cite this
ETF Copilot, “XBI vs XLV holdings overlap and scores”, as of October 28, 2026.
https://etf-copilot.com/compare/xbi-vs-xlv
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