XBI vs XLV: holdings overlap, shared companies and scores
As of September 11, 2026, XBI and XLV overlap 7.5% by weight. State Street SPDR S&P Biotech ETF (XBI): U.S. biotech industry stocks. State Street Health Care Select Sector SPDR ETF (XLV): U.S. healthcare sector.
Updated September 11, 2026
How much do XBI and XLV overlap?
As of September 11, 2026, XBI and XLV overlap 7.5% by weight.
11% of XBI is already inside XLV.
19% of XLV is already inside XBI.
XBI holds 145 companies and XLV holds 59; 8 are in both.
Computed by ETF Copilot from both funds' holdings rather than quoted from a data provider, and rebuilt nightly.
How does ETF Copilot score XBI and XLV?
As of September 11, 2026, ETF Copilot scores XBI 2.7 out of 10 and XLV 5.5 out of 10.
They differ most on Growth: XBI 1.6 and XLV 7.9.
The five factor scores behind them are set out below, 0–10 and higher is better, ranked against every US equity ETF we track.
| Factor | XBI | XLV |
|---|---|---|
| Growth | 1.6 | 7.9 |
| Risk | 1.4 | 7.4 |
| Quality | 2.5 | 4.7 |
| Return | 4.7 | 3.6 |
XLV is the cheaper of the two at 0.08% a year
As of September 11, 2026, XBI charges 0.35% a year, yields 0.15% and holds $11.3B in assets across 145 positions.
As of September 11, 2026, XLV charges 0.08% a year, yields 1.80% and holds $43.4B in assets across 59 positions.
| Measure | XBI | XLV |
|---|---|---|
| Expense ratio | 0.35% | 0.08% |
| Dividend yield | 0.15% | 1.80% |
| Assets under management | $11.3B | $43.4B |
| Holdings | 145 | 59 |
Expense ratio, dividend yield and assets under management are reported by the fund and refreshed daily. Every other figure on this page is computed by ETF Copilot.
Where XBI and XLV trade against their own history
XBI trades at 23.3 times earnings, against its own median of 17.7, and is more expensive than 79% of its own 114 monthly readings since 2017.
XLV trades at 30.3 times earnings, against its own median of 24.7, and is more expensive than 87% of its own 114 monthly readings since 2017.
What moved XBI and XLV this week
XBI fell 5.0% in the week to September 11, 2026. The holdings that moved it most were Dyne Therapeutics (−27.0%), Sellas Life Sciences (−15.7%) and Amgen (−15.0%); Roivant Sciences (+18.6%) pushed the other way.
XLV fell 4.6% in the week to September 11, 2026. The holdings that moved it most were Eli Lilly (−3.8%), Amgen (−15.0%) and Johnson & Johnson (−4.6%); HCA Healthcare (+4.3%) pushed the other way.
What do XBI and XLV each hold?
16% of XBI is its ten largest holdings.
What's inside XLV: AI 0%.
61% of XLV is its ten largest holdings.
Compare with similar funds
Cite this
ETF Copilot, “XBI vs XLV holdings overlap and scores”, as of September 11, 2026.
https://etf-copilot.com/compare/xbi-vs-xlv
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