IXJ vs XBI: holdings overlap, shared companies and scores

As of September 11, 2026, IXJ and XBI overlap 6.9% by weight. iShares Global Healthcare ETF (IXJ): Global healthcare sector stocks. State Street SPDR S&P Biotech ETF (XBI): U.S. biotech industry stocks.

Updated September 11, 2026

How much do IXJ and XBI overlap?

As of September 11, 2026, IXJ and XBI overlap 6.9% by weight.

15% of IXJ is already inside XBI.

11% of XBI is already inside IXJ.

IXJ holds 121 companies and XBI holds 145; 8 are in both.

Computed by ETF Copilot from both funds' holdings rather than quoted from a data provider, and rebuilt nightly.

How does ETF Copilot score IXJ and XBI?

As of September 11, 2026, ETF Copilot scores IXJ 5.4 out of 10 and XBI 2.7 out of 10.

They differ most on Risk: IXJ 7.2 and XBI 1.4.

The five factor scores behind them are set out below, 0–10 and higher is better, ranked against every US equity ETF we track.

IXJ vs XBI — ETF Copilot factor scores, 0–10
Factor	IXJ	XBI
Growth	6.8	1.6
Valuation	5.9	—
Risk	7.2	1.4
Quality	5.7	2.5
Return	2.2	4.7

XBI is the cheaper of the two at 0.35% a year

As of September 11, 2026, IXJ charges 0.38% a year, yields 1.81% and holds $4.3B in assets across 121 positions.

As of September 11, 2026, XBI charges 0.35% a year, yields 0.15% and holds $11.3B in assets across 145 positions.

IXJ vs XBI — cost, income and size
Measure	IXJ	XBI
Expense ratio	0.38%	0.35%
Dividend yield	1.81%	0.15%
Assets under management	$4.3B	$11.3B
Holdings	121	145

Expense ratio, dividend yield and assets under management are reported by the fund and refreshed daily. Every other figure on this page is computed by ETF Copilot.

Where IXJ and XBI trade against their own history

IXJ trades at 26.5 times earnings, against its own median of 24.1, and is more expensive than 81% of its own 114 monthly readings since 2017.

XBI trades at 23.3 times earnings, against its own median of 17.7, and is more expensive than 79% of its own 114 monthly readings since 2017.

What moved IXJ and XBI this week

IXJ fell 5.0% in the week to September 11, 2026. The holdings that moved it most were Novartis (−15.2%), Amgen (−15.0%) and Eli Lilly (−3.8%); HCA Healthcare (+4.3%) pushed the other way.

XBI fell 5.0% in the week to September 11, 2026. The holdings that moved it most were Dyne Therapeutics (−27.0%), Sellas Life Sciences (−15.7%) and Amgen (−15.0%); Roivant Sciences (+18.6%) pushed the other way.

What do IXJ and XBI each hold?

What's inside IXJ: AI 0%.

46% of IXJ is its ten largest holdings.

16% of XBI is its ten largest holdings.

Compare with similar funds

Cite this

ETF Copilot, “IXJ vs XBI holdings overlap and scores”, as of September 11, 2026.
https://etf-copilot.com/compare/ixj-vs-xbi