IXJ vs XBI: holdings overlap, shared companies and scores
As of October 28, 2026, IXJ and XBI overlap 8.9% by weight. iShares Global Healthcare ETF (IXJ): Global healthcare sector stocks. State Street SPDR S&P Biotech ETF (XBI): U.S. biotech industry stocks.
Updated October 28, 2026
Where IXJ trades against its own history
IXJ trades at 29.7 times earnings, against its own median of 24.8, and is more expensive than 93% of its own last 9 years.
What moved IXJ and XBI this week
IXJ rose 0.5% in the week to October 28, 2026. The holdings that moved it most were Johnson & Johnson (+5.1%), Genmab A/S (+46.4%) and Eli Lilly (+1.4%); Merck (−6.0%) pushed the other way.
XBI rose 3.1% in the week to October 28, 2026. The holdings that moved it most were Oruka Therapeutics (+20.1%), Twist Bioscience (+16.3%) and Grail (+19.1%); Moderna (−12.9%) pushed the other way.
What do IXJ and XBI each hold?
What's inside IXJ: AI 0%.
48% of IXJ is its ten largest holdings.
18% of XBI is its ten largest holdings.
How much do IXJ and XBI overlap? 8.9% by weight
As of October 28, 2026, IXJ and XBI overlap 8.9% by weight.
15% of IXJ is already inside XBI.
13% of XBI is already inside IXJ.
IXJ holds 123 companies and XBI holds 163; 8 are in both.
Computed by ETF Copilot from both funds' holdings rather than quoted from a data provider, and rebuilt nightly.
How does ETF Copilot score IXJ and XBI? 5.1 and 4.9 out of 10
As of October 28, 2026, ETF Copilot scores IXJ 5.1 out of 10 and XBI 4.9 out of 10.
They differ most on Quality: IXJ 7.2 and XBI 0.3.
The five factor scores behind them are set out below, 0–10 and higher is better, ranked against every US equity ETF we track.
| Factor | IXJ | XBI |
|---|---|---|
| Growth | 5.2 | 9.8 |
| Value | 1.9 | — |
| Risk | 8.1 | 1.2 |
| Quality | 7.2 | 0.3 |
| Return | 3.8 | 5.6 |
XBI is the cheaper of the two at 0.35% a year
As of October 28, 2026, IXJ charges 0.38% a year, yields 1.33% and holds $4.5B in assets across 123 positions.
As of October 28, 2026, XBI charges 0.35% a year, yields 0.35% and holds $10.3B in assets across 163 positions.
| Measure | IXJ | XBI |
|---|---|---|
| Expense ratio | 0.38% | 0.35% |
| Dividend yield | 1.33% | 0.35% |
| Assets under management | $4.5B | $10.3B |
| Holdings | 123 | 163 |
Expense ratio, dividend yield and assets under management are reported by the fund and refreshed daily. Every other figure on this page is computed by ETF Copilot.
Compare with similar funds
Cite this
ETF Copilot, “IXJ vs XBI holdings overlap and scores”, as of October 28, 2026.
https://etf-copilot.com/compare/ixj-vs-xbi
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