ETF Copilot

FBT vs XBI: holdings overlap, shared companies and scores

As of October 28, 2026, FBT and XBI overlap 25.9% by weight. First Trust NYSE Arca Biotechnology Index Fund (FBT): U.S. biotech stocks. State Street SPDR S&P Biotech ETF (XBI): U.S. biotech industry stocks.

Updated October 28, 2026

Where FBT trades against its own history

FBT trades at 31.9 times earnings, against its own median of 21.1, and is more expensive than 94% of its own last 6 years.

What moved FBT and XBI this week

FBT rose 2.6% in the week to October 28, 2026. The holdings that moved it most were Genmab A/S (+44.8%), Veracyte (+8.8%) and TG Therapeutics (+7.9%); Corcept Therapeutics (−25.8%) pushed the other way.

XBI rose 3.1% in the week to October 28, 2026. The holdings that moved it most were Oruka Therapeutics (+20.1%), Twist Bioscience (+16.3%) and Grail (+19.1%); Moderna (−12.9%) pushed the other way.

What do FBT and XBI each hold?

36% of FBT is its ten largest holdings.

18% of XBI is its ten largest holdings.

How much do FBT and XBI overlap? 25.9% by weight

As of October 28, 2026, FBT and XBI overlap 25.9% by weight.

62% of FBT is already inside XBI.

26% of XBI is already inside FBT.

FBT holds 30 companies and XBI holds 163; 18 are in both.

Computed by ETF Copilot from both funds' holdings rather than quoted from a data provider, and rebuilt nightly.

How does ETF Copilot score FBT and XBI? 5.4 and 4.9 out of 10

As of October 28, 2026, ETF Copilot scores FBT 5.4 out of 10 and XBI 4.9 out of 10.

They differ most on Risk: FBT 4.1 and XBI 1.2.

The five factor scores behind them are set out below, 0–10 and higher is better, ranked against every US equity ETF we track.

FBT vs XBI — ETF Copilot factor scores, 0–10
FactorFBTXBI
Growth9.89.8
Value0.2—
Risk4.11.2
Quality2.00.3
Return7.65.6

XBI is the cheaper of the two at 0.35% a year

As of October 28, 2026, FBT charges 0.55% a year and holds $3.0B in assets across 30 positions.

As of October 28, 2026, XBI charges 0.35% a year, yields 0.35% and holds $10.3B in assets across 163 positions.

FBT vs XBI — cost, income and size
MeasureFBTXBI
Expense ratio0.55%0.35%
Dividend yield—0.35%
Assets under management$3.0B$10.3B
Holdings30163

Expense ratio, dividend yield and assets under management are reported by the fund and refreshed daily. Every other figure on this page is computed by ETF Copilot.

Compare with similar funds

Cite this

ETF Copilot, “FBT vs XBI holdings overlap and scores”, as of October 28, 2026.
https://etf-copilot.com/compare/fbt-vs-xbi

  1. First Trust NYSE Arca Biotechnology Index Fund (FBT)
  2. State Street SPDR S&P Biotech ETF (XBI)

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