GNOM vs ITOT: holdings overlap, shared companies and scores
As of October 9, 2026, GNOM and ITOT overlap 2.5% by weight. Global X Genomics & Biotechnology ETF (GNOM): Global genomics and biotech firms. iShares Core S&P Total U.S. Stock Market ETF (ITOT): U.S. total market equities.
Updated October 9, 2026
Where ITOT trades against its own history
ITOT trades at 24.2 times earnings, against its own median of 22.3, and is more expensive than 63% of its own last 9 years.
What moved GNOM and ITOT this week
GNOM fell 1.2% in the week to October 9, 2026. The holdings that moved it most were Twist Bioscience (−15.3%), 10X Genomics (−13.7%) and Guardant Health (−5.8%); Moderna (+18.4%) pushed the other way.
ITOT rose 1.0% in the week to October 9, 2026. The holdings that moved it most were Microsoft (+3.4%), Amazon.com (+4.3%) and Alphabet (+2.4%); Nvidia (−2.0%) pushed the other way.
What do GNOM and ITOT each hold?
What's inside GNOM: AI 3%, Tech 0%.
55% of GNOM is its ten largest holdings.
What's inside ITOT: Tech 43%, Magnificent 7 31%.
35% of ITOT is its ten largest holdings.
How much do GNOM and ITOT overlap? 2.5% by weight
As of October 9, 2026, GNOM and ITOT overlap 2.5% by weight.
86% of GNOM is already inside ITOT.
3% of ITOT is already inside GNOM.
GNOM holds 50 companies and ITOT holds 2,425; 41 are in both.
Computed by ETF Copilot from both funds' holdings rather than quoted from a data provider, and rebuilt nightly.
How does ETF Copilot score GNOM and ITOT? 3.6 and 6.6 out of 10
As of October 9, 2026, ETF Copilot scores GNOM 3.6 out of 10 and ITOT 6.6 out of 10.
They differ most on Quality: GNOM 0.1 and ITOT 7.7.
The five factor scores behind them are set out below, 0–10 and higher is better, ranked against every US equity ETF we track.
| Factor | GNOM | ITOT |
|---|---|---|
| Growth | 7.8 | 7.2 |
| Risk | 0.5 | 6.3 |
| Quality | 0.1 | 7.7 |
| Return | 3.9 | 7.7 |
ITOT is the cheaper of the two at 0.03% a year
As of October 9, 2026, GNOM charges 0.50% a year, yields 0.94% and holds $98M in assets across 50 positions.
As of October 9, 2026, ITOT charges 0.03% a year, yields 0.99% and holds $97.8B in assets across 2425 positions.
| Measure | GNOM | ITOT |
|---|---|---|
| Expense ratio | 0.50% | 0.03% |
| Dividend yield | 0.94% | 0.99% |
| Assets under management | $98M | $97.8B |
| Holdings | 50 | 2425 |
Expense ratio, dividend yield and assets under management are reported by the fund and refreshed daily. Every other figure on this page is computed by ETF Copilot.
Compare with similar funds
Cite this
ETF Copilot, “GNOM vs ITOT holdings overlap and scores”, as of October 9, 2026.
https://etf-copilot.com/compare/gnom-vs-itot
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