XBI vs ITOT ETF Comparison
State Street SPDR S&P Biotech ETF (XBI): U.S. biotech industry stocks. iShares Core S&P Total US Stock Market ETF (ITOT): U.S. total market equities.
14% of XBI is its ten largest holdings.
33% of ITOT is its ten largest holdings.
2% of ITOT is already inside XBI.
100% of XBI is already inside ITOT.
Overlap by weight: 2.3%.
As of July 2026, ETF Copilot compares XBI vs ITOT on Value, Growth, Quality, and Risk.
Updated July 2026
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